In the Sanskrit pratitya samutpada is a direct reference to "dependent origination," or in other words: things do exist in some way but nothing exists on its own, and nothing can be its own cause.
Everything is in some way interdependent with the rest of the world and what the world is trying to achieve with us being around to observe it all in the first place.
The so-called external things can only exist in relation to one another, never in and of themselves.
All visible and invisible characteristics of natural phenomena are defined only through relationships.
One relationship leads to the other giving the appearance of being connected, conditioned and in turn conditioning.